Contractile Reserve in Dilated Cardiomyopathy
نویسندگان
چکیده
Dilated cardiomyopathy (DCM) is one of the most common types of cardiomyopathy worldwide. It is characterized by progressive chamber dilatation and myocardial systolic dysfunction and diagnosed by finding left ventricular (LV) enlargement and impaired systolic LV function (LV ejection fraction less than 50% or fractional shortening of less than 25-30%). Angiotensin-converting enzyme inhibitors and ß-blockers are the best and popular therapeutic interventions for DCM that promotes amelioration of systolic LV dysfunction among 20-45% DCM patients [1 5]; nonetheless, the 5-year mortality rate of DCM remains 10-35% under these medical therapy [6 8].
منابع مشابه
Temporal changes in plasma brain natriuretic peptide levels during exercise stress-echocardiography in patients with dilated cardiomyopathy.
The aim of this study was to evaluate temporal changes in brain natriuretic petide (BNP) levels during exercise stress-echocardiography in patients with dilated cardiomyopathy with respect to the left ventricular contractile reserve. We studied 55 consecutive patients with dilated cardiomyopathy (mean age, 55 ± 10 years, 49 (89.1%) male). All patients underwent exercise stress-echocardiography ...
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OBJECTIVE Patients with non-ischaemic systolic heart failure (HF) and idiopathic dilated cardiomyopathy (DCM) are a heterogenous group with varied morbidity and mortality. Prognostication in this group is challenging. We performed a systematic review and meta-analysis to examine the significance of the presence of contractile reserve as assessed via stress imaging on mortality and hospitalisati...
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INTRODUCTION AND OBJECTIVES Myocardial contractile reserve studies with low-dose dobutamine echocardiography have been shown to be useful to assess functional myocardial status. However, the variables associated with contractile reserve after inotropic stimulation are not well known. PATIENTS AND METHOD We studied 50 patients (35 men, mean age 56.4 +/- 9.5 years) with nonischemic dilated card...
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A number of studies have suggested that stress-echocardiography may be used for prognostic stratification in patients with idiopathic dilated cardiomyopathy. There is no consensus on which protocol or which measurements of left ventricular contractile reserve to use. The most frequently used protocol is low-dose dobutamine stress-echocardiography, and most commonly used measures of left ventric...
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OBJECTIVES The purpose of this study was to assess regional coronary flow and contractile reserve in patients with idiopathic dilated cardiomyopathy (IDCM). BACKGROUND Although IDCM has been associated with alterations in coronary blood flow and contractile reserve, little is known about their regional distribution and correlation. METHODS Fourteen patients with IDCM and 11 control subjects...
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BACKGROUND Left ventricular (LV) dyssynchrony is not a stable phenomenon, but rather, changes dynamically. Given that the prognostic impact of dynamic dyssynchrony has not yet been elucidated, the objective was to investigate the clinical impact of dynamic dyssynchrony on patients with dilated cardiomyopathy (DCM). METHODS AND RESULTS Seventy DCM patients with ejection fraction 32±9% were ret...
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